Users are not able to connect to GlobalProtect with the error message: "Could not connect to the GlobalProtect service."

• Unable to connect to GlobalProtect Portal/Gateway
• GlobalProtect App GUI shows the intermittent errors listed below.
  • Could not connect to the GlobalProtect service
  • Gateway <GW name>: The network connection is unreachable, or the gateway is unresponsive. Check the network connection and reconnect.
• PanGPS logs show the connection failing at the portal or gateway pre-login, with error the message.

(P7512-T7760)Debug(3731):  12/01/25 10:11:41:639 ----Gateway Pre-login starts---- 
(P7512-T7760)Debug(14013): 12/01/25 10:11:41:639 Check cert of server 192.168.1.100 
(P7512-T7760)Info ( 166):  12/01/25 10:11:41:640 SSL_CTX_new() failed: error retrieving entropy 
(P7512-T7760)Debug(14028): 12/01/25 10:11:41:640 File C:\Program Files\Palo Alto Networks\GlobalProtect\tca.cer does not exist. 
(P7512-T7760)Debug( 939):  12/01/25 10:11:41:640 SSL connecting to 192.168.1.100 
(P7512-T7760)Debug( 584):  12/01/25 10:11:41:670 Network is reachable 
(P7512-T7760)Error( 449):  12/01/25 10:11:41:694 Server error: Create SSL context failed 
(P7512-T7760)Debug( 956):  12/01/25 10:11:41:694 connect() failed 
(P7512-T7760)Error(14060): 12/01/25 10:11:41:694 ConnectSSL: Failed to connect to '192.168.1.100:443'. Disconnect ssl. 
(P7512-T7760)Debug(14111): 12/01/25 10:11:41:694 Cannot get server cert of 192.168.1.100 
(P7512-T7760)Debug(6870):  12/01/25 10:11:41:694 Already tried both ipv4 and ipv6 for gateway test-vpngw.com 
(P7512-T7760)Error(3817):  12/01/25 10:11:41:694 Failed to connect to gateway test-vpngw.com. 
(P7512-T7760)Debug(6197):  12/01/25 10:11:41:695 Show Gateway Testvpn-GW: The network connection is unreachable or the gateway is unresponsive. Check the network connection and reconnect.

• PAN-OS
• AMD64 Family Processors
• GlobalProtect Gateway
• GlobalProtect Portal

Software Issue.

1. The issue is resolved under GPC-24048
2. Upgrading to the fixed versions of  6.3.3-h4 (6.3.3-c828) and 6.2.8-h5 (6.2.8-c416)  will resolve the issue.