Unable to connect to Prisma Access in Proxy only mode when Cisco Anyconnect is connected

• GlobalProtect App on macOS disconnects frequently when Cisco AnyConnect VPN was enabled.
• The issue is not seen on Windows devices with Cisco AnyConnect.
• The GlobalProtect App is configured in Proxy mode.

• GlobalProtect: App on macOS
• Proxy mode
• Cisco AnyConnect
• Explicit Proxy

macOS failed to r redirect the DNS requests passing through the AnyConnect UTUN interface.

The workaround for this is to set IP only based rule in forward profile for the Explicit Proxy configuration.

• Check the following CLI output for both anyconnect connected and anyconnect disconnected.

netstat -rn
traceroute <Proxy Domain>
curl -vvI "https://Proxy URL"

• You will fine that anyconnect does not exclude connection to proxy server when connected.
• From the curl command, when anyconnect is connected, the SSL connection is blocked.